Meissner cells

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Meissner Corpuscles are a type of neuron found in mammals.

Contents

1 NS neuron

2 Anatomy

3 Molecular profile

4 Physiology

4.1 Synaptic Connections

4.1.1 Synaptic Inputs

4.1.2 Synaptic Outputs

4.2 Spiking properties

5 Behavior

6 References

7 Additional information

1: NS neuron

2: Anatomy

Meissner Corpuscles are a type of somatosensory neuron that are approximately 0.02 mm long and 0.01 mm wide. They are located along the glabrous skin in the dermis. As a dorsal root ganglion neuron, it can be sensitive to noxious stimuli and have small-diameter axons that are either myelinated or unmyelinated.

3: Molecular profile

4: Physiology

Meissner corpuscles are rapidly adapting cells that are sensitive to touch and pressure.

4:1 Synaptic Connections

4:1:1 Synaptic Inputs

Sensory neurons send action potentials to the central nervous system that inhibit motor neurons.

4:1:2 Synaptic Outputs

4:2 Spiking properties

Meissner cells are rapidly adapting. They respond to a continous stimulus by firing a burst of action potentials to mark the beginning and ending of the stimulus. They respond quickly at first but then stop firing even though the stimulus continues. Encapsulated axon terminals act as a filter to shape the mechanoreceptor's response to a stimulus.

5: Behavior

Meissner cells respond to transient, phasic, or vibratory stimuli.

6: References

1.Bear, Mark F., Connors, Barry W., Paradiso, Michael A., 2007, Neuroscience: Exploring the Brain.

2.Hoffman, Joscelyn N., Montag, Anthony G., Dominy, Nathaniel J., (2004), Meissner Corpuscles and Somatosensory Acuity: The Prehensile Appendages of Primates and Elephants., The Anatomical Record Part A 281A:1138-1147.

3.Martin, John Harry, Neuroanatomy:Text and Atlas, 114-117.

7: Additional information

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