Amphid Neurons

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Amphid Neuron is a neuron in C. elegans.

Basic information

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Amphid neurons are chemosensory neurons found in C. elegans. Each amphid sensory neuron expresses a specific set of candidate receptor genes and detects a characteristic set of attractants, repellents, or pheromones. About 500-1000 different G protein-coupled receptors (GPCRs) are expressed in chemosensory neurons(Bargmann CI). Chemosensory neurons generally belong to bilaterally symmetric pairs in which the left and right members of each class are structurally similar. Each left-right pair forms a class that can be distinguished from all other classes based on cilium morphology, axon morphology, and synaptic targets (White et al., 1986).. Amphid Neuron: Sensory Neuron, Motor Neuron, local interneuron, projection neuron, etc...


As with most other neuron classes, amphid sensory neuron classes consist of one pair of two bilaterally symmetric cells (see also B). Each of the 12 pairs of amphid sensory neurons extends a dendrite to the tip of the nose and an axon into the nerve ring, a nerve bundle where synaptic connections are made (WHITE et al. 1986). Amphid sensory neuron classes consist of two bilaterally symmetric pairs of neurons, two of which, AWCL/R and ASEL/R, are functionally lateralized. While some other amphid sensory neurons appear to contribute to gustation, ASE is the main gustatory neuron class in C. elegans, mediating responses to salts, amino acids, and small metabolites (BARGMANN and HORVITZ 1991).

  • Where is the Cell body located?
  • What is the axon projection pattern?
  • How many neurons of this type are there in the nervous system?

Molecular profile

  • Neurotransmitter: ____________
  • Unique molecular markers: ______________


Synaptic Connections

Synaptic Inputs

Synaptic Outputs

Spiking properties



  1. Author1 FM,Author2 FM (year) Title, Journal, vol: pages. PMID.
  2. Author1 FM,Author2 FM (year) Title, Journal, vol: pages. PMID.

Additional information

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