Common spiny neuron

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Common Spiny Neuron, CSN, is a frequently occurring neuron in the bed nuclei of the stria terminalis oval nucleus.


Its main function is as an inhibitory neuron that interacts with other spiny neurons to inhibit each other. They accomplish this through the use of GABA


The somata is oval or star shaped. The dendrites have about two to three branches and these branches are covered by tiny spines.

Molecular profile

It releases the neurotransmitter GABA.


It is unquie in that it can rest at two different thresholds. One called the "up" period where it rest at about -50mV to -55mV. During this period its easily excited. The down period is where its not as easily excited and the membrane potential is less. This was witnessed in anesthetized animals.

Synaptic Inputs

The input is from other CSN through the release of GABA.

Synaptic Outputs

It self-regulates other CSN through its release of GABA.

Spiking properties

Its biphasic "up" and "down" periods make it unique to other neuron and there firing patterns.


Models of information processing in the basal ganglia By James C. Houk, Joel L. Davis, David G. Beiser. (This reference is incomplete --Pkatz 20:36, 24 September 2009 (UTC))

The Brain Architecture Management System [1]