Cochlea hair cell

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Cochlea Hair Cell is a neuron located in the cochlea of the inner ear of mammals and some nonmammals such as birds

NS neuron

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There are two types of cochlea hair cells, outside hair cells and inside hair cells. They both assist in the process of relaying sound to the brain. These cells are found in a small area in the cochlea called the organ of Corti. Anywhere from 17,500-23,500 hair cells can be found in the human ear. Each cell is covered by special structures called stereocilia, a primary structure used in sound transduction. With stimulation, the stereocilia bend which cause a signal that goes to the auditory nerve and eventually to the auditory cortex allowing sound to be processed by the brain.

Neuronal Type: Mechanoreceptor cells

Anatomy

The cochlear hair cells are located in the organ of Corti, a small organ found in the scala media within the cochlea in the ear. Hair cells sit on the basilar membrane and have an overhead cover called the reticular lamina. Two structures called the rods of Corti support the reticular lamina and the basilar membrane. Directly above the reticular lamina is the tectorial membrane. Each hair cell consists of many cilia called stereocilia. These structures sit on top of the cell and can be found touching the tectorial membrane and/or the reticular lamina. One cilium is longer than the rest, and this cilium is called the kinocilium. The direction of the movement of the kinocilium determines whether the cell depolarizes or hyperpolarizes. There are two types of cochlear hair cells, outer hair cells and inner hair cells. Inner hair cells are far less in number, approximately 3500, then outer hair cells which can number up to 20,000 in each ear. Both cells are innervated by the spiral ganglion which transmit signals to the auditory nerve and eventually to the auditory cortex in the brain.

Molecular profile

  • Neurotransmitter: ____________
  • Unique molecular markers: Stereocilia

Physiology

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Synaptic Connections

Synaptic Inputs

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Synaptic Outputs

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Spiking properties

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Behavior

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References

1. Kwan T., White PM, and Segil N. (2009) "Development and Regeneration of the Inner Ear", Annals of the New York Academy of Sciences vol 1170:28-33.

2. Lewis G. Tilney, David J. Derosier, and Michael J. Mulroy (1980)"The organization of actin filaments in the stereocilia of cochlear hair cells", The Journal of Cell Biology, Vol 86, 244-259.

  1. Author1 FM,Author2 FM (year) Title, Journal, vol: pages. PMID.
  2. Author1 FM,Author2 FM (year) Title, Journal, vol: pages. PMID.

Additional information

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