Difference between revisions of "Olfactory bulb mitral cell"

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[[Contents]]  
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== Basic information ==
1 Basic information
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[[Image:EavBinDown.gif|thumb|This needs a description and a citation]]
2 Anatomy
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Principal neuron located in the olfactory bulb in the mammalian central nervous system. In the olfactory bulb, cell bodies are arranged in a thin mitral cell body layer between the granule cell layer and the external plexiform layer. Each mitral cell is characterized usually by a single primary dendrite that traverses the external plexiform layer and terminates within an olfactory glomerulus in a tuft of branches where they receive input from the axons of olfactory receptor neurons. Axons of the mitral cells transfer information to a number of areas in the brain, including the piriform cortex, entorhinal cortex, olfactory tubercle, and amygdala (Shepherd, 1).
3 Molecular profile
 
4 Physiology
 
4.1 Synaptic Connections
 
4.1.1 Synaptic Inputs
 
4.1.2 Synaptic Outputs
 
4.2 Spiking properties
 
5 Behavior
 
6 References
 
7 Additional information
 
 
[[Basic information]]
 
  
The olfactory bulb is a group of nuerons which communicate with nuerons and bascially functions as the brains smelling center. The combination of odors and create reponses in the sensory nuerons these sensory nuerons then transmit this information to the olfactory bulb. The brain then can interpret these smells. The interpretation of these smells eventually leads to the storage of these smells and memory of this chemical responses.  
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The cell soma’s shape is a Bishop's mitre, or cap-shaped, and measures 10-15 um. The dendrites of the cell are located in the glomerular and external plexiform layer.(Neurolex, 2).
  
Within the olfactory bulb is a very important type of cell, the Olfactory bulb mitral cell. The olfactory bulb mitral cell is of great imporatance.
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'''Neuronal Type:''' Sensory Neuron
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'''Species:''' Mammals
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'''Other Names:''' Mitral neuron, Mitral cell
  
[[Structure]]
 
  
According to an article in the comparative journal of nuerobiology the structure of the mitral cell in the olfactory bulb has been deduced by using goldfish.
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== Anatomy ==
  
These cells typically have appendages which are considered to be round and at times even triangular in shape. They often have cylindrical shafts and dendrites. These cells form synapses at various parts of the cell.
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Located in the layer between the granule cell layer and the external plexiform layer of the olfactory bulb.
  
[[Image:EavBinDown.gif|thumb|Description]]
 
  
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== Molecular profile ==
  
[[Neuronal Type:]] Sensory Neuron:
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'''Neurotransmitter:''' Glutamate
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Some studies have suggested that endogenous glutamate tonically modulates mitral cell excitability and responsiveness to olfactory nerve input,and hence the operation of the mitral olfactory bulb circuitry, via activation of mGluR1.
  
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== Physiology ==
  
[[References]]
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The olfactory bulb mitral cells are apical, sparsely branching and 300-500 um length. The apical tuft is richly branching in glomerulus (100-200 um) and the basal (lateral) is sparsely branching (up to 1 mm in length).
  
"Linda Buck," Microsoft® Encarta® Online Encyclopedia 2008
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== Synaptic Connections ==
http://encarta.msn.com © 1997-2008 Microsoft Corporation. All Rights Reserved.
 
  
http://senselab.med.yale.edu/NeuronDB/ndbEavSum.asp?id=267
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=== Synaptic Inputs ===
  
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Synapses formed by the olfactory nerve (ON) provide the source of excitatory synaptic input onto mitral cells (MC) in the olfactory bulb. These synapses, which relay odor-specific inputs, are confined to the distally tufted single primary dendrites of MCs, the first stage of central olfactory processing (Yuan et al., 3).
  
link title
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=== Synaptic Outputs ===
  
Retrieved from "http://neuronbank.org/wiki/index.php/Template"
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Axons of the mitral cells transfer information to a number of areas in the brain, including the piriform cortex, entorhinal cortex, olfactory tubercle, and amygdala.
Category: User contributed neurons
 
  
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== Spiking properties ==
  
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Regular Spiker
  
This work is licensed under a Creative Commons Attribution 3.0 Unported License.
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== Behavior ==
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The olfactory bulb mitral cell is involved in the processing of information pertaining to odors and the sense of smell.
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== References ==
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1. Shepherd, G. M. The synaptic organization of the brain, ed 5 New York: Oxford University Press, 2004.
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2.    [http://www.neurolex.org/wiki/Category:Olfactory_bulb_main_mitral_cell NeuroLex: Olfactory_bulb_main_mitral_cell]
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3. Calcium Signaling in Mitral Cell Dendrites of Olfactory Bulbs of Neonatal Rats and Mice During Olfactory Nerve Stimulation and β-Adrenoceptor Activation. Qi Yuan, Hiroki Mutoh, Franck Debarbieux, and Thomas Knöpfel.Learn. Mem. 2004. 11: 406-411.
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[[Category: User contributed neurons]]
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[[Category: Biol6102 student pages]]

Latest revision as of 15:23, 22 September 2009

Basic information

This needs a description and a citation

Principal neuron located in the olfactory bulb in the mammalian central nervous system. In the olfactory bulb, cell bodies are arranged in a thin mitral cell body layer between the granule cell layer and the external plexiform layer. Each mitral cell is characterized usually by a single primary dendrite that traverses the external plexiform layer and terminates within an olfactory glomerulus in a tuft of branches where they receive input from the axons of olfactory receptor neurons. Axons of the mitral cells transfer information to a number of areas in the brain, including the piriform cortex, entorhinal cortex, olfactory tubercle, and amygdala (Shepherd, 1).

The cell soma’s shape is a Bishop's mitre, or cap-shaped, and measures 10-15 um. The dendrites of the cell are located in the glomerular and external plexiform layer.(Neurolex, 2).

Neuronal Type: Sensory Neuron Species: Mammals Other Names: Mitral neuron, Mitral cell


Anatomy

Located in the layer between the granule cell layer and the external plexiform layer of the olfactory bulb.


Molecular profile

Neurotransmitter: Glutamate Some studies have suggested that endogenous glutamate tonically modulates mitral cell excitability and responsiveness to olfactory nerve input,and hence the operation of the mitral olfactory bulb circuitry, via activation of mGluR1.

Physiology

The olfactory bulb mitral cells are apical, sparsely branching and 300-500 um length. The apical tuft is richly branching in glomerulus (100-200 um) and the basal (lateral) is sparsely branching (up to 1 mm in length).

Synaptic Connections

Synaptic Inputs

Synapses formed by the olfactory nerve (ON) provide the source of excitatory synaptic input onto mitral cells (MC) in the olfactory bulb. These synapses, which relay odor-specific inputs, are confined to the distally tufted single primary dendrites of MCs, the first stage of central olfactory processing (Yuan et al., 3).

Synaptic Outputs

Axons of the mitral cells transfer information to a number of areas in the brain, including the piriform cortex, entorhinal cortex, olfactory tubercle, and amygdala.

Spiking properties

Regular Spiker


Behavior

The olfactory bulb mitral cell is involved in the processing of information pertaining to odors and the sense of smell.

References

1. Shepherd, G. M. The synaptic organization of the brain, ed 5 New York: Oxford University Press, 2004. 2. NeuroLex: Olfactory_bulb_main_mitral_cell 3. Calcium Signaling in Mitral Cell Dendrites of Olfactory Bulbs of Neonatal Rats and Mice During Olfactory Nerve Stimulation and β-Adrenoceptor Activation. Qi Yuan, Hiroki Mutoh, Franck Debarbieux, and Thomas Knöpfel.Learn. Mem. 2004. 11: 406-411.