Purkinje neuron

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This is a mock up of a general page on Purkinje Neurons.

Drawing of Purkinje cells (A) and granule cells (B) from pigeon cerebellum by Santiago Ramón y Cajal, 1899. Instituto Santiago Ramón y Cajal, Madrid, Spain.


Purkinje cells (or Purkinje neurons) are a class of GABAergic neuron located in the cerebellar cortex.

Inputs and Outputs

Purkinje Neurons receive inputs from parallel fibers and climbing fibers. They output to the deep cerebellar nuclei.



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  2. Sugihara I. Organization and remodeling of the olivocerebellar climbing fiber projection. Cerebellum. 2006;5(1):15-22. Review. PMID: 16527759
  3. Beierlein M, Regehr WG. Conventional synapses for unconventional cells. Neuron. 2005 Jun 2;46(5):694-6. Review. PMID: 15924854
  4. Hartmann J, Konnerth A. Determinants of postsynaptic Ca2+ signaling in Purkinje neurons. Cell Calcium. 2005 May;37(5):459-66. Review. PMID: 15820394
  5. Schmolesky MT, De Zeeuw CI, Hansel C. Climbing fiber synaptic plasticity and modifications in Purkinje cell excitability. Prog Brain Res. 2005;148:81-94. Review. PMID: 15661183