Purkinje neuron

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This is a mock up of a general page on Purkinje Neurons.

Drawing of Purkinje cells (A) and granule cells (B) from pigeon cerebellum by Santiago Ramón y Cajal, 1899. Instituto Santiago Ramón y Cajal, Madrid, Spain.

Description

Purkinje cells (or Purkinje neurons) are a class of GABAergic neuron located in the cerebellar cortex.


Inputs and Outputs

Purkinje Neurons receive inputs from parallel fibers and climbing fibers. They output to the deep cerebellar nuclei.


Links


References

  1. Lee KJ, Kim H, Rhyu IJ. The roles of dendritic spine shapes in Purkinje cells. Cerebellum. 2005;4(2):97-104. Review. PMID: 16035191
  2. Sugihara I. Organization and remodeling of the olivocerebellar climbing fiber projection. Cerebellum. 2006;5(1):15-22. Review. PMID: 16527759
  3. Beierlein M, Regehr WG. Conventional synapses for unconventional cells. Neuron. 2005 Jun 2;46(5):694-6. Review. PMID: 15924854
  4. Hartmann J, Konnerth A. Determinants of postsynaptic Ca2+ signaling in Purkinje neurons. Cell Calcium. 2005 May;37(5):459-66. Review. PMID: 15820394
  5. Schmolesky MT, De Zeeuw CI, Hansel C. Climbing fiber synaptic plasticity and modifications in Purkinje cell excitability. Prog Brain Res. 2005;148:81-94. Review. PMID: 15661183